Repair & Recovery

TB-500 (TB4)

SKU NA-027CAS 77591-33-4MW 4963.4
99.75% HPLCThird-party testedRUO · Research use only

Price range: $49.98 through $65.98

White solid. CAS 77591-33-4, MW 4963.4. Reconstitute with bacteriostatic water. Purity 99.75% by RP-HPLC. Research use only — not for human or veterinary use.

Multi-vial pricing
HPLC verifiedPurity confirmed per lot
COA includedLot-specific certificate
Cold-chainShipped 2-8°C with packs
Lot traceableDocumented to dispatch
RUOThis product is sold for laboratory research use only. It is not a drug or supplement and is not for human or veterinary consumption, diagnostic or therapeutic use.
Description

TB-500 (TB4) is a thymosin β-4 / synthetic fragment supplied by Nano Aminos strictly as a reference material for in-vitro and laboratory research. It is catalogued under CAS 77591-33-4, molecular formula C212H350N56O78S, and a molecular weight of 4963.4 g/mol.

Provided as a lyophilized powder (white solid), TB-500 (TB4) is part of the Nano Aminos Repair & Recovery research range and is prepared for research use by reconstitution in bacteriostatic water using standard aseptic technique.

Every production lot is characterized by reversed-phase HPLC and mass spectrometry at 99.75% typical HPLC purity and ships with a lot-specific Certificate of Analysis (COA), so identity and purity can be independently confirmed before use. Vials are kept cold and protected from repeated freeze–thaw cycles. TB-500 (TB4) is available in 5 mg and 10 mg research sizes.

Related research: browse the full Repair & Recovery category or compare KLOW (TB+BPC+KPV+GHK) and Thymalin.

For research use only. Not for human or veterinary use. TB-500 (TB4) is not a drug, food, or dietary supplement.

Specifications
CompoundTB-500 (TB4)
ClassificationThymosin β-4 / synthetic fragment
CAS number77591-33-4
Molecular formulaC212H350N56O78S
Molecular weight4963.4 g/mol
Purity99.75% by RP-HPLC (area %)
Physical formLyophilized powder
AppearanceWhite solid
ReconstitutionBacteriostatic water
Lab documentation

Each production lot is released against an analytical specification and ships with the corresponding Certificate of Analysis.

Certificate of analysis

TB-500 (TB4) 5 mg

Lot 262557853
Purity (HPLC-UV)
99.75%
Identity (LC-MS)
Confirmed
Net content
5.55 mg/vial
Appearance
White to off-white lyophilised powder
Method
HPLC-UV with LC-MS confirmation
Reported
6 Aug 2026
Accession
AD-5061-5699-3069
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Opens on this page. Analysis by an independent laboratory. Research use only - not for human or veterinary use.

Storage & handling

Storage. Store lyophilized material at -20°C protected from light and moisture for long-term stability. After reconstitution, keep at 2-8°C and use within the documented in-use window.

Handling. Allow sealed vials to equilibrate to room temperature before opening to limit condensation. Reconstitute with the listed diluent using standard aseptic laboratory technique. Avoid repeated freeze-thaw cycles.

Safety. Handle as a laboratory research chemical. Wear appropriate PPE and follow your institution's chemical-handling and waste-disposal procedures.

Shipping

Dispatch. In-stock orders are processed on business days and shipped with temperature-controlled packaging and gel packs to preserve material integrity in transit.

Tracking. A tracking reference is issued at dispatch. Lab accounts can consolidate shipments and arrange standing orders.

Eligibility. Orders are accepted from researchers, resellers and institutions for laboratory research use only.

Selected research

Literature referencing this compound.

Publications relevant to this molecule, provided for research reference. Inclusion does not imply an approved use or any claim about the products sold here.

Review
Expert Opin Biol Ther. 2012;12(1):37–51
Thymosin β4: a multi-functional regenerative peptide — basic properties and clinical applications
Goldstein AL, Hannappel E, Sosne G, Kleinman HK.
Review
Trends Mol Med. 2005;11(9):421–429
Thymosin β4: actin-sequestering protein moonlights to repair injured tissues
Goldstein AL, Hannappel E, Kleinman HK.
Preclinical/clinical
Vitam Horm. 2016;102:251–275
Thymosin β4 Promotes Dermal Healing
Kleinman HK, Sosne G.
Reference

Background reading on peptide chemistry and handling.